Advanced Practice Locums Updated February 24, 2025

By Editorial Team

10 Unusual Nurse Practitioner Jobs

The field is evolving faster than ever, and nurse practitioners (NPs) are in high demand across the country. The AANP predicts a remarkable 45% growth in nurse practitioner jobs between 2023 and 2033, highlighting the rapid and sustained expansion of this profession.  

But while many nurse practitioners work in traditional settings—such as hospitals, clinics, or private practices—the opportunities for adventurous NPs extend far beyond the norm.  

If you’re a nurse practitioner looking for a unique career path that perfectly blends your skills with something unconventional, this list is for you. From working at horse racing venues to delivering care via telehealth, these unusual NP jobs might just inspire your next career move. 

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Exploring “Unusual” NP Jobs 

Unlike traditional roles, these positions allow NPs to step outside their routine scope of practice. Whether it’s using locum tenens jobs for flexibility or blending creativity into medical care, these unique roles showcase the versatility of nurse practitioners.  

Here’s our updated list of the 10 most intriguing NP career paths for 2025.  

1. Horse Racing Venues  

Imagine working at a racetrack—not as a spectator or gambler, but as a trusted healthcare provider for staff. NPs at horse racing venues like the Kentucky Racing Health Services Center ensure that jockeys, stable hands, and other staff members stay healthy.  

Why Consider It? Many workers in this industry are uninsured or part of underserved communities, presenting nurse practitioners with a meaningful way to make an impact. 

2. Mobile Medical Units for the Homeless  

Taking healthcare on the road, mobile clinics like Orlando’s HOPE Mobile Unit serve homeless populations by delivering primary care directly to underserved areas.  

Why Consider It? This role combines clinical expertise with social outreach, offering immense satisfaction by meeting patients where they are.  

3. World Trade Center Health Program  

Nurse practitioners play a vital role in programs like the WTC Health Program at Mount Sinai, which provides ongoing medical care to first responders and others affected by the September 11 attacks.  

Why Consider It? If you're passionate about providing specialized, long-term care to individuals affected by disasters, this multidisciplinary setting is ideal.  

See Also
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4. Medical Writing and Education  

Love sharing your expertise? Nurse practitioners can thrive as writers, editors, or consultants, creating continuing education materials, editing journals, or consulting for healthcare companies.  

Why Consider It? This role offers the opportunity to work remotely, share your knowledge, and contribute to advancing the field of nursing education.  

5. Caring for At-Risk Youth  

Programs like Orlando Health’s Teen Xpress provide free healthcare to uninsured and underinsured students in middle and high schools. From physical exams to mental health counseling, these programs offer comprehensive care.  

Why Consider It? This job gives nurse practitioners the chance to intervene early in the lives of at-risk youth, profoundly impacting their health and future.  

6. Telehealth and Virtual Care  

The rise of telehealth has greatly expanded opportunities for nurse practitioners. NPs can now deliver behavioral healthcare from remote locations through telehealth platforms.  

Why Consider It? Telehealth offers unparalleled flexibility, making it easier to work part-time, eliminate commutes, or care for patients across the country. 

7. Medical Aesthetics and Cosmetic Procedures  

Nurse practitioners often work in dermatology clinics or medical spas, delivering services such as Botox injections, laser treatments, and dermal fillers.  

Why Consider It? If you're seeking a creative outlet where you can help people feel their best, medical aesthetics might blend medicine and artistry perfectly.  

8. Locum Tenens Assignments  

For NPs looking for adventure, locum tenens roles provide short-term assignments in diverse settings. These positions allow for travel to different locations while maintaining a flexible schedule.  

Why Consider It? Locum tenens offers both work-life balance and the opportunity to explore different roles and regions before committing to a permanent position.  

9. Retail Clinics  

Retail clinics, often within pharmacies or stores, are growing in popularity due to their convenience. These clinics operate extended hours, offering nurse practitioners options for part-time or full-time roles.  

Why Consider It? Retail clinics provide access to more flexible shifts while addressing straightforward medical needs in a fast-paced yet manageable environment.  

10. Rural Practice  

For NPs seeking to make a significant difference, rural areas offer opportunities to provide care in underserved communities. Roughly 15% of NPs practice in towns with fewer than 10,000 residents.  

Why Consider It? The need for healthcare is often greatest in rural settings, where nurse practitioners can enjoy autonomy and make meaningful connections with their tight-knit patient communities.  

The Advantages of Pursuing a Non-Traditional NP Job 

These unusual nurse practitioner jobs highlight the versatility of the NP profession. By stepping into non-traditional roles, nurse practitioners often unlock more than just unique career experiences—they gain flexibility, the chance to work across communities, and the ability to impact diverse populations.  

Whether you enjoy combining travel with work through locum tenens or prefer facing new challenges in telehealth, the range of options is virtually endless.  

How to Land One of These Jobs  

Interested in one of these unique roles? Follow these steps to get started:  

Network and Research  

Use online platforms to research employers actively hiring for non-traditional NP roles. Sites like AMN Healthcare offer numerous options in locum tenens and other niches. 

Tailor Your Resume  

Highlight transferable skills, and be sure to emphasize any specialized training or certifications that align with these unique positions.  

Be Open to Relocation  

Certain roles, such as rural practice or mobile clinics, may require you to be geographically flexible.  

Partner with Recruiters  

Recruitment agencies specializing in advanced practice roles can simplify the job search process and connect you with opportunities perfectly suited to your goals.  

Discover What’s Next in Your NP Career  

With such a wide variety of opportunities, nurse practitioners have endless paths to grow their careers while making a difference. Whether you're looking for adventure, flexibility, or a way to give back, there’s an unusual NP job waiting for you in 2025.  

If you're ready to take the next step, AMN Healthcare can help you find roles that fit your expertise, lifestyle, and aspirations—including locum tenens positions and permanent jobs.

Apply Now

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